Review of a Pathological Condition Essay Example | Topics and Well Written Essays - 1500 words

Review of a Pathological Condition - Essay Example In this case, the most probable cause for these symptoms could be uncontrolled diabetes mellitus or/and other long standing endocrine disorders therefore co-morbidities, leading to complications or death due to not being treated appropriately. The review of these pathological conditions, are presented by discussing categories of common causes of symptoms and disease progression, most susceptible individuals, utilising diagnostic imaging procedures for treatment and prognosis. Causes of the symptoms Genetics, environmental factors, poor diet, obesity, medications, infections and sedentary lifestyle have been cited by Chapman and Nakielny (2009) and William and Christine (2005) as some of the possible causes of diabetes as indicated in Richard and Neil (2007). Diabetics require strict dietary control to minimise the impact on lifestyle, as observed by Launer (2009) as the body fails to produce or utilise insulin properly. The islets of Langerhans of the pancreas contain four types of c ells, but two cells, alpha cells producing glucagon, which opposes insulin and beta cells responsible for producing insulin (Scobie, 2007). In Type 1 diabetes, there is a lack of insulin with only glucagon present inducing hyperglycemia. With the absence of insulin to absorb glucose in the bloodstream to metabolise complex sugars, glucose levels in the body increases leading to uncontrolled diabetes with hyperglycemia affecting the kidneys. The abnormal structural condition of this individual with a plethora of signs and symptoms, i.e., diabetes, fatigue, an insufficiency fracture of the femoral neck, oliguria and pruritus, all indicating uncontrolled diabetes leading to renal failure attributing to calcium/mineral abnormalities and toxicity in the body. Parathyroid disorders may also exacerbate the condition if this is present or initiated through renal failure. Disease Progression Diabetes is a group of metabolic diseases with characteristic hyperglycemia associated with defects i n insulin secretion, insulin action, or both (Launer, 2009). Type 1 diabetes is characterized by beta cell destruction, usually leading to absolute insulin deficiency. Type 2 diabetes on the other hand presents as a spectrum of metabolic abnormalities with prominent insulin resistance and relative insulin deficiency (William and Christine, 2005). The effect of diabetes is not limited to carbohydrate metabolism, but lipid and protein metabolism play an important role in its progression as noted by Launer (2009). Diabetic progression is initiated through numerous metabolic events that occur over a period of years. Repeated hyperglycemic attacks or chronic hyperglycemia, results in damage to other organs such as the kidneys leading to other complications or death. Hyperglycemia affects the kidneys causing diabetic nephropathy and glomerular filtration reduction. This result in the following manifestations: uncontrolled diabetes causing renal failure, resulting in oliguria, pruritus, fa tigue and insufficiency fractures. It is a chain effect. Controlling metabolic events make it possible to slow or stop the progression of the disease. There are three main types of diabetes. The symptoms are similar although there are differences in the way they develop. In Type 1 diabetes, the signs and symptoms are usually very obvious and can develop